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A phase I study of nelfinavir concurrent with temozolomide and radiotherapy in patients with glioblastoma multiforme

We conducted a phase I trial to examine the maximally tolerated dose (MTD) of the oral protease inhibitor nelfinavir (NFV) in combination with temozolomide and concurrent radiotherapy in patients with glioblastoma and to gather preliminary data for response. The study was conducted in patients with...

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Hlavní autoři: Alonso-Basanta, Michelle, Fang, Penny, Maity, Amit, Hahn, Stephen M., Lustig, Robert A., Dorsey, Jay F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116080/
https://ncbi.nlm.nih.gov/pubmed/24194293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-013-1303-3
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