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Podocyte-Specific VEGF-A Gain of Function Induces Nodular Glomerulosclerosis in eNOS Null Mice

VEGF-A and nitric oxide are essential for glomerular filtration barrier homeostasis and are dysregulated in diabetic nephropathy. Here, we examined the effect of excess podocyte VEGF-A on the renal phenotype of endothelial nitric oxide synthase (eNOS) knockout mice. Podocyte-specific VEGF(164) gain...

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Detalhes bibliográficos
Main Authors: Veron, Delma, Aggarwal, Pardeep K., Velazquez, Heino, Kashgarian, Michael, Moeckel, Gilbert, Tufro, Alda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116059/
https://ncbi.nlm.nih.gov/pubmed/24578128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013070752
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