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Dual HER2-targeting without chemotherapy and estrogen deprivation in the neoadjuvant setting

Trastuzumab has had a major impact on outcomes in HER2-positive breast cancer, but innate or acquired resistance to it is recognized as a problem that can limit its effectiveness. Given its locus of action, the oral tyrosine kinase inhibitor lapatinib would be expected to counteract many of the prop...

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Détails bibliographiques
Auteur principal: Sikov, William M.
Format: Artigo
Langue:Inglês
Publié: AME Publishing Company 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115768/
https://ncbi.nlm.nih.gov/pubmed/25083500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2227-684X.2013.09.01
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