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25-Hydroxycholesterol acts as an amplifier of inflammatory signaling

Cross-talk between sterol regulatory pathways and inflammatory pathways has been demonstrated to significantly impact the development of both atherosclerosis and infectious disease. The oxysterol 25-hydroxycholesterol (25HC) plays multiple roles in lipid biosynthesis and immunity. We recently used a...

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Detalhes bibliográficos
Main Authors: Gold, Elizabeth S., Diercks, Alan H., Podolsky, Irina, Podyminogin, Rebecca L., Askovich, Peter S., Treuting, Piper M., Aderem, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115544/
https://ncbi.nlm.nih.gov/pubmed/24994901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404271111
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