Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

The Ras/MAPK signaling cascade regulates various biological functions, including cell growth and proliferation. As such, this pathway is frequently deregulated in several types of cancer, including most cases of melanoma. RSK (p90 ribosomal S6 kinase) is a MAPK-activated protein kinase required for...

詳細記述

保存先:
書誌詳細
主要な著者: Galan, Jacob A., Geraghty, Kathryn M., Lavoie, Geneviève, Kanshin, Evgeny, Tcherkezian, Joseph, Calabrese, Viviane, Jeschke, Grace R., Turk, Benjamin E., Ballif, Bryan A., Blenis, John, Thibault, Pierre, Roux, Philippe P.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
PNAS Plus
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115529/
https://ncbi.nlm.nih.gov/pubmed/25002506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405601111
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