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Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study.

We have determined the conformation of the channel-forming polypeptide antibiotic gramicidin A in phosphatidylcholine vesicles by using 13C and 19F NMR spectroscopy. The models previously proposed for the conformation of the dimer channel differ in the surface localization of the NH2 and COOH termin...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Weinstein, S, Wallace, B A, Blout, E R, Morrow, J S, Veatch, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1979
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/92025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4230
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