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Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study.

We have determined the conformation of the channel-forming polypeptide antibiotic gramicidin A in phosphatidylcholine vesicles by using 13C and 19F NMR spectroscopy. The models previously proposed for the conformation of the dimer channel differ in the surface localization of the NH2 and COOH termin...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Weinstein, S, Wallace, B A, Blout, E R, Morrow, J S, Veatch, W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/92025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4230
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