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A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a
β-Diguetoxin-Dc1a (Dc1a) is a toxin from the desert bush spider Diguetia canities that incapacitates insects at concentrations that are non-toxic to mammals. Dc1a promotes opening of German cockroach voltage-gated sodium (Na(v)) channels (BgNa(v)1), whereas human Na(v) channels are insensitive. Here...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115291/ https://ncbi.nlm.nih.gov/pubmed/25014760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5350 |
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