Catch and Release: Photocleavable Cationic Diblock Copolymers as a Potential Platform for Nucleic Acid Delivery

Binding interactions between DNA and cationic carriers must be sufficiently strong to prevent nuclease-mediated degradation, yet weak enough to permit transcription. We demonstrate cationic diblock copolymers containing PEG and o-nitrobenzyl moieties that facilitated tailorable DNA complexation and...

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Autori principali: Green, Matthew D., Foster, Abbygail A., Greco, Chad T., Roy, Raghunath, Lehr, Rachel M., Epps, Thomas H., Sullivan, Millicent O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115287/
https://ncbi.nlm.nih.gov/pubmed/25090637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4PY00638K
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