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A Single Mutation in the Acetylcholine Receptor δ-Subunit Causes Distinct Effects in Two Types of Neuromuscular Synapses

Mutations in AChR subunits, expressed as pentamers in neuromuscular junctions (NMJs), cause various types of congenital myasthenic syndromes. In AChR pentamers, the adult ε subunit gradually replaces the embryonic γ subunit as the animal develops. Because of this switch in subunit composition, mutat...

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Main Authors: Park, Jee-Young, Mott, Meghan, Williams, Tory, Ikeda, Hiromi, Wen, Hua, Linhoff, Michael, Ono, Fumihito
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115133/
https://ncbi.nlm.nih.gov/pubmed/25080583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0426-14.2014
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