Improved Efficacy and Reduced Toxicity of Doxorubicin Encapsulated in Sulfatide-Containing Nanoliposome in a Glioma Model

As a glycosphingolipid that can bind to several extracellular matrix proteins, sulfatide has the potential to become an effective targeting agent for tumors overexpressing tenasin-C in their microenvironment. To overcome the dose-limiting toxicity of doxorubicin (DOX), a sulfatide-containing nanolip...

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Autori principali: Lin, Jia, Shigdar, Sarah, Fang, Ding Zhi, Xiang, Dognxi, Wei, Ming Q., Danks, Andrew, Kong, Lingxue, Li, Lianghong, Qiao, Liang, Duan, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114873/
https://ncbi.nlm.nih.gov/pubmed/25072631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103736
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