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Shikonin promotes autophagy in BXPC-3 human pancreatic cancer cells through the PI3K/Akt signaling pathway

The present study aimed to investigate the effect of shikonin on autophagy in BXPC-3 human pancreatic cancer cells and its underlying mechanism. Cell viability was assessed using the Cell Counting Kit-8 assay and the expression of light chain (LC) 3, p62, phosphoinositide 3-kinase (PI3K), Akt, phosp...

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Autori principali: SHI, SHUQING, CAO, HAIMEI
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114587/
https://ncbi.nlm.nih.gov/pubmed/25120662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2293
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