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Production of a recombinant vaccine candidate against Burkholderia pseudomallei exploiting the bacterial N-glycosylation machinery

Vaccines developing immune responses toward surface carbohydrates conjugated to proteins are effective in preventing infection and death by bacterial pathogens. Traditional production of these vaccines utilizes complex synthetic chemistry to acquire and conjugate the glycan to a protein. However, gl...

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Hlavní autoři: Garcia-Quintanilla, Fatima, Iwashkiw, Jeremy A., Price, Nancy L., Stratilo, Chad, Feldman, Mario F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114197/
https://ncbi.nlm.nih.gov/pubmed/25120536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00381
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