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Chronicles of a death foretold: Dual sequential cell death checkpoints in TNF signaling
The kinase RIP1 wears a coat of many colors during TNF receptor signaling and can regulate both activation of pro-survival NFκB and programmed cell death pathways. In this review, we outline how coating RIP1 with K63-linked ubiquitin chains forms a protective layer that prevents RIP1 from binding ap...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114106/ https://ncbi.nlm.nih.gov/pubmed/20237426 |
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