Loss of nuclear PTEN in HCV-infected human hepatocytes

BACKGROUND: Hepatitis C virus (HCV) infection is a major risk factor for chronic hepatitis and hepatocellular carcinoma (HCC); however, the mechanism of HCV-mediated hepatocarcinogenesis is not well understood. Insufficiency of PTEN tumor suppressor is associated with more aggressive cancers, includ...

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Hlavní autoři: Bao, Wenjie, Florea, Liliana, Wu, Ningbin, Wang, Zhao, Banaudha, Krishna, Qian, Jason, Houzet, Laurent, Kumar, Rakesh, Kumar, Ajit
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114100/
https://ncbi.nlm.nih.gov/pubmed/25075209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-9-23
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