Mechanism of Hepatitis C Virus (HCV)-induced Osteopontin and Its Role in Epithelial to Mesenchymal Transition of Hepatocytes

Osteopontin (OPN) is a secreted phosphoprotein, originally characterized in malignant-transformed epithelial cells. OPN is associated with tumor metastasis of several tumors and is overexpressed in hepatocellular carcinoma (HCC) tissue involving HCC invasion and metastasis. Importantly, OPN is signi...

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Bibliografiske detaljer
Main Authors: Iqbal, Jawed, McRae, Steven, Banaudha, Krishna, Mai, Thi, Waris, Gulam
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873557/
https://ncbi.nlm.nih.gov/pubmed/24240095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492314
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