The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo.

The interferon-inducible double-stranded (ds) RNA-activated protein kinase (PKR) exhibits antiviral, anticellular, and antitumor activities. The mechanisms of its enzymatic activation by autophosphorylation and of the observed transdominant inhibitory phenotype of enzymatically inactive mutants have...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Patel, R C, Stanton, P, McMillan, N M, Williams, B R, Sen, G C
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC41141/
https://ncbi.nlm.nih.gov/pubmed/7545299
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