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New strategies with anti-IgE in allergic diseases
IgE has long been known as a therapeutic target for allergic disease, but the difficulty has been in selecting agents that don't trigger cross linkage of IgE when bound to its high affinity receptor (FceR1) on mast cells and basophils. By “designing” a monoclonal antibody (mAb) which targets th...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
World Allergy Organization
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114087/ https://ncbi.nlm.nih.gov/pubmed/25097719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1939-4551-7-17 |
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