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New strategies with anti-IgE in allergic diseases
IgE has long been known as a therapeutic target for allergic disease, but the difficulty has been in selecting agents that don't trigger cross linkage of IgE when bound to its high affinity receptor (FceR1) on mast cells and basophils. By “designing” a monoclonal antibody (mAb) which targets th...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
World Allergy Organization
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114087/ https://ncbi.nlm.nih.gov/pubmed/25097719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1939-4551-7-17 |
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