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Cardiac Resynchronization Therapy Improves Altered Na Channel Gating in Canine Model of Dyssynchronous Heart Failure
BACKGROUND: Slowed Na(+) current (I(Na)) decay and enhanced late I(Na) (I(Na-L)) prolong the action potential duration (APD) and contribute to early afterdepolarizations (EADs). Cardiac resynchronization therapy (CRT) shortens APD compared to dyssynchronous heart failure (DHF), however, the role of...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114055/ https://ncbi.nlm.nih.gov/pubmed/23650309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.113.000400 |
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