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A Bidirectional System for the Dynamic Small Molecule Control of Intracellular Fusion Proteins
Small molecule control of intracellular protein levels allows temporal and dose-dependent regulation of protein function. Recently, we developed a method to degrade proteins fused to a mutant dehalogenase (HaloTag2) using small molecule hydrophobic tags (HyTs). Here, we introduce a complementary met...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113957/ https://ncbi.nlm.nih.gov/pubmed/23978068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400569k |
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