Differential roles of microglia and monocytes in the inflamed central nervous system

In the human disorder multiple sclerosis (MS) and in the model experimental autoimmune encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their numbers correlate to tissue damage. Macrophages may be derived from infiltrating monocytes or resident microglia, yet are indistingu...

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Detalhes bibliográficos
Main Authors: Yamasaki, Ryo, Lu, Haiyan, Butovsky, Oleg, Ohno, Nobuhiko, Rietsch, Anna M., Cialic, Ron, Wu, Pauline M., Doykan, Camille E., Lin, Jessica, Cotleur, Anne C., Kidd, Grahame, Zorlu, Musab M., Sun, Nathan, Hu, Weiwei, Liu, LiPing, Lee, Jar-Chi, Taylor, Sarah E., Uehlein, Lindsey, Dixon, Debra, Gu, Jinyu, Floruta, Crina M., Zhu, Min, Charo, Israel F., Weiner, Howard L., Ransohoff, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113947/
https://ncbi.nlm.nih.gov/pubmed/25002752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132477
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