Modulation of the CXC Chemokine Receptor 4 Agonist Activity of Ubiquitin through C-Terminal Protein Modification

[Image: see text] Extracellular ubiquitin has recently been described as a CXC chemokine receptor (CXCR) 4 agonist. Studies on the structure–function relationship suggested that the C-terminus of ubiquitin facilitates CXCR4 activation. It remains unknown, however, whether C-terminal processing of ub...

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Main Authors: Tripathi, Abhishek, Saini, Vikas, Marchese, Adriano, Volkman, Brian F., Tang, Wei-Jen, Majetschak, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113718/
https://ncbi.nlm.nih.gov/pubmed/23697661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400254f
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