Structural Determinants of Ubiquitin-CXC Chemokine Receptor 4 Interaction

Ubiquitin, a post-translational protein modifier inside the cell, functions as a CXC chemokine receptor (CXCR) 4 agonist outside the cell. However, the structural determinants of the interaction between extracellular ubiquitin and CXCR4 remain unknown. Utilizing C-terminal truncated ubiquitin and ub...

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Bibliografiske detaljer
Main Authors: Saini, Vikas, Marchese, Adriano, Tang, Wei-Jen, Majetschak, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243501/
https://ncbi.nlm.nih.gov/pubmed/22039044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298505
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