Experimental and Computational Studies of Physicochemical Properties Influence NSAID-Cyclodextrin Complexation

The objective of this research was to investigate physicochemical properties of an active pharmaceutical ingredient (API) that influence cyclodextrin complexation through experimental and computational studies. Native β-cyclodextrin (B-CD) and two hydroxypropyl derivatives were first evaluated by co...

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Autors principals: Felton, Linda A., Popescu, Carmen, Wiley, Cody, Esposito, Emilio Xavier, Lefevre, Philippe, Hopfinger, Anton J.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113631/
https://ncbi.nlm.nih.gov/pubmed/24718709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0110-2
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