Defining the Critical Material Attributes of Lactose Monohydrate in Carrier Based Dry Powder Inhaler Formulations Using Artificial Neural Networks

The study aimed to establish a function-based relationship between the physical and bulk properties of pre-blended mixtures of fine and coarse lactose grades with the in vitro performance of an adhesive active pharmaceutical ingredient (API). Different grades of micronised and milled lactose (Lactoh...

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Hlavní autoři: Kinnunen, Hanne, Hebbink, Gerald, Peters, Harry, Shur, Jagdeep, Price, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113628/
https://ncbi.nlm.nih.gov/pubmed/24831088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0108-9
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