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Characterization of the Prostate-Specific Antigen (PSA) Catalytic Mechanism: A Pre-Steady-State and Steady-State Study

Prostate-specific antigen (PSA), an enzyme of 30 kDa grouped in the kallikrein family is synthesized to high levels by normal and malignant prostate epithelial cells. Therefore, it is the main biomarker currently used for early diagnosis of prostate cancer. Here, presteady-state and steady-state kin...

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Detalhes bibliográficos
Main Authors: Tomao, Luigi, Sbardella, Diego, Gioia, Magda, Di Masi, Alessandra, Marini, Stefano, Ascenzi, Paolo, Coletta, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113483/
https://ncbi.nlm.nih.gov/pubmed/25068395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102470
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