Klf4 Regulates the Expression of Slurp1, Which Functions as an Immunomodulatory Peptide in the Mouse Cornea

PURPOSE. The secreted Ly6/uPAR-related protein-1 (Slurp1), associated with the hyperkeratotic disorder mal de Meleda, is abundantly expressed in corneas. Here, we examine its corneal expression and functions. METHODS. Gene expression was quantified by quantitative PCR (qPCR), immunoblots, and immuno...

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Hlavní autoři: Swamynathan, Sudha, Buela, Kristine-Ann, Kinchington, Paul, Lathrop, Kira L., Misawa, Hidemi, Hendricks, Robert L., Swamynathan, Shivalingappa K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113333/
https://ncbi.nlm.nih.gov/pubmed/23139280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10759
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