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Klf4 Regulates the Expression of Slurp1, Which Functions as an Immunomodulatory Peptide in the Mouse Cornea

PURPOSE. The secreted Ly6/uPAR-related protein-1 (Slurp1), associated with the hyperkeratotic disorder mal de Meleda, is abundantly expressed in corneas. Here, we examine its corneal expression and functions. METHODS. Gene expression was quantified by quantitative PCR (qPCR), immunoblots, and immuno...

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Detalhes bibliográficos
Main Authors: Swamynathan, Sudha, Buela, Kristine-Ann, Kinchington, Paul, Lathrop, Kira L., Misawa, Hidemi, Hendricks, Robert L., Swamynathan, Shivalingappa K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113333/
https://ncbi.nlm.nih.gov/pubmed/23139280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10759
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