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Phosphorylation of α-Tubulin by Protein Kinase C Stimulates Microtubule Dynamics in Human Breast Cells

Protein kinase C (PKC) engenders motility through phosphorylation of α-tubulin at Ser-165 in non-transformed MCF-10A cells. Live cell imaging explored the impact of PKC-mediated phosphorylation on microtubule (MT) dynamics. MTs fluorescently labeled with GFP-α-tubulin were treated with diacylglycero...

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Detalhes bibliográficos
Main Authors: De, Shatarupa, Tsimounis, Areti, Chen, Xiangyu, Rotenberg, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113324/
https://ncbi.nlm.nih.gov/pubmed/24574051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21167
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