Impacts of Hypoxia-Inducible Factor-1 Knockout in the Retinal Pigment Epithelium on Choroidal Neovascularization

PURPOSE. Hypoxia-inducible factor (HIF)-1 is a key oxygen sensor and is believed to play an important role in neovascularization (NV). The purpose of this study is to determine the role of retinal pigment epithelium (RPE)-derived HIF-1α on ocular NV. METHODS. Conditional HIF-1α knockout (KO) mice we...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Mingkai, Hu, Yang, Chen, Ying, Zhou, Kevin K., Jin, Ji, Zhu, Meili, Le, Yun-Zheng, Ge, Jian, Ma, Jian-xing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113187/
https://ncbi.nlm.nih.gov/pubmed/22915031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8936
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