Impacts of Hypoxia-Inducible Factor-1 Knockout in the Retinal Pigment Epithelium on Choroidal Neovascularization

PURPOSE. Hypoxia-inducible factor (HIF)-1 is a key oxygen sensor and is believed to play an important role in neovascularization (NV). The purpose of this study is to determine the role of retinal pigment epithelium (RPE)-derived HIF-1α on ocular NV. METHODS. Conditional HIF-1α knockout (KO) mice we...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lin, Mingkai, Hu, Yang, Chen, Ying, Zhou, Kevin K., Jin, Ji, Zhu, Meili, Le, Yun-Zheng, Ge, Jian, Ma, Jian-xing
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2012
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113187/
https://ncbi.nlm.nih.gov/pubmed/22915031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8936
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi