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Causes and consequences of centrosome abnormalities in cancer

Centrosome amplification is a hallmark of cancer. However, despite significant progress in recent years, we are still far from understanding how centrosome amplification affects tumorigenesis. Boveri's hypothesis formulated more than 100 years ago was that aneuploidy induced by centrosome ampli...

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Библиографические подробности
Главные авторы: Godinho, S. A., Pellman, D.
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113111/
https://ncbi.nlm.nih.gov/pubmed/25047621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0467
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