A Comprehensive and High Resolution Genome-wide Response of p53 to Stress

Tumor-suppressor p53 regulates transcription of stress response genes. Many p53 targets remain undiscovered due to uncertainty as to where p53 binds in the genome, and that few genes reside near p53-bound recognition elements (REs). Using ChIP-exo, we associated p53 with 2,183 unsplit REs. REs were...

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Hauptverfasser: Chang, Gue Su, Chen, Xiangyun Amy, Park, Bongsoo, Rhee, Ho Sung, Li, Pingxin, Han, Kang Hoo, Mishra, Tejaswini, Chan-Salis, Ka Yim, Li, Yunfei, Hardison, Ross C., Wang, Yanming, Pugh, B. Franklin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113076/
https://ncbi.nlm.nih.gov/pubmed/25043190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.030
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