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ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple Negative Breast Cancer Cells

We previously reported that a pan-PAD inhibitor YW3-56 activates p53 target genes to inhibit cancer growth. However, the p53-independent anticancer activity and molecular mechanisms of YW3-56 remain largely elusive. Here, gene expression analyses found that ATF4 target genes involved in ER stress re...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Wang, Shu, Chen, Xiangyun Amy, Hu, Jing, Jiang, Jian-kang, Li, Yunfei, Chan-Salis, Ka Yim, Gu, Ying, Chen, Gong, Thomas, Craig, Pugh, B. Franklin, Wang, Yanming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394025/
https://ncbi.nlm.nih.gov/pubmed/25612620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-1093-T
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