Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis

Hyaluronan (HA) is an extracellular matrix glycosaminoglycan that is present in pancreatic islets, but little is known about its involvement in the development of human type 1 diabetes (T1D). We have evaluated whether pancreatic islets and lymphoid tissues of T1D and nondiabetic organ donors differ...

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Bibliographic Details
Main Authors: Bogdani, Marika, Johnson, Pamela Y., Potter-Perigo, Susan, Nagy, Nadine, Day, Anthony J., Bollyky, Paul L., Wight, Thomas N.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2014
Subjects:
Islet Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113060/
https://ncbi.nlm.nih.gov/pubmed/24677718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1658
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