Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice

AIM: To test the role of mast cells in gut inflammation and colitis using interleukin (IL)-10-deficient mice as an experimental model. METHODS: Mast cell-deficient (Kit(W-sh/W-sh)) mice were crossbred with IL-10-deficient mice to obtain double knockout (DKO) mice. The growth, mucosal damage and coli...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Hanying, Xue, Yansong, Wang, Hui, Huang, Yan, Du, Min, Yang, Qiyuan, Zhu, Mei-Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Inc 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112873/
https://ncbi.nlm.nih.gov/pubmed/25083083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i27.9106
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