In vitro blood cell responsiveness to IFN-α predicts clinical response independently of IL28B in hepatitis C virus genotype 1 infected patients

BACKGROUND: Treatment with interferon-alpha (IFN-α) and ribavirin successfully clears hepatitis C virus (HCV) infection in 50% of patients infected with genotype 1. Addition of NS3-4A protease inhibitors (PIs) increases response rates but results in additional side effects and significant economic c...

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Detalhes bibliográficos
Main Authors: Bourke, Nollaig M, O’Neill, Mary-Teresa, Sarwar, Shahzad, Norris, Suzanne, Stewart, Stephen, Hegarty, John E, Stevenson, Nigel J, O’Farrelly, Cliona
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112837/
https://ncbi.nlm.nih.gov/pubmed/25048205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-206
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