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Mutation affecting thermostability of sigma subunit of Escherichia coli RNA polymerase lies near the dnaG locus at about 66 min on the E. coli genetic map.

The Escherichia coli strain, ts-rnp5, originally described in 1975 by G. D. Burdick and H. Berger, is shown to possess an RNA polymerase (RNA nucleotidyltransferase) sigma subunit with an activity 4--6 times less thermostable at 45 degrees than sigma from wild-type strains. This defect remains assoc...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Gross, C, Hoffman, J, Ward, C, Hager, D, Burdick, G, Berger, H, Burgess, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1978
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/343110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.427
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