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Mutation affecting thermostability of sigma subunit of Escherichia coli RNA polymerase lies near the dnaG locus at about 66 min on the E. coli genetic map.

The Escherichia coli strain, ts-rnp5, originally described in 1975 by G. D. Burdick and H. Berger, is shown to possess an RNA polymerase (RNA nucleotidyltransferase) sigma subunit with an activity 4--6 times less thermostable at 45 degrees than sigma from wild-type strains. This defect remains assoc...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gross, C, Hoffman, J, Ward, C, Hager, D, Burdick, G, Berger, H, Burgess, R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411262/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/343110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.427
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