DDX39B (BAT1), TNF and IL6 gene polymorphisms and association with clinical outcomes of patients with Plasmodium vivax malaria

BACKGROUND: DDX39B (BAT1) encodes an RNA helicase known to regulate expression of TNF and IL-6. Elevated levels of these two cytokines are associated with increased severity of clinical malaria. The aim of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs)...

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Main Authors: Mendonça, Vitor RR, Souza, Ligia CL, Garcia, Gabriela C, Magalhães, Belisa ML, Lacerda, Marcus VG, Andrade, Bruno B, Gonçalves, Marilda S, Barral-Netto, Manoel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112608/
https://ncbi.nlm.nih.gov/pubmed/25038626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-278
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