Associations between hepcidin and immune response in individuals with hyperbilirubinaemia and severe malaria due to Plasmodium vivax infection

BACKGROUND: Hyperbilirubinaemia (bilirubin >51.3 μmol/L) alone is not indicative of severe malaria, and the immune response underlying hyperbilirubinaemia remains largely unexplored. Liver damage associated with hyperbilirubinaemia may alter the expression of hepcidin, which regulates systemic ir...

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Vydáno v:Malar J
Hlavní autoři: Mendonça, Vitor R. R., Souza, Ligia C. L., Garcia, Gabriela C., Magalhães, Belisa M. L., Gonçalves, Marilda S., Lacerda, Marcus V. G., Barral-Netto, Manoel
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607001/
https://ncbi.nlm.nih.gov/pubmed/26466783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0930-x
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