Associations between hepcidin and immune response in individuals with hyperbilirubinaemia and severe malaria due to Plasmodium vivax infection

BACKGROUND: Hyperbilirubinaemia (bilirubin >51.3 μmol/L) alone is not indicative of severe malaria, and the immune response underlying hyperbilirubinaemia remains largely unexplored. Liver damage associated with hyperbilirubinaemia may alter the expression of hepcidin, which regulates systemic ir...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Mendonça, Vitor R. R., Souza, Ligia C. L., Garcia, Gabriela C., Magalhães, Belisa M. L., Gonçalves, Marilda S., Lacerda, Marcus V. G., Barral-Netto, Manoel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607001/
https://ncbi.nlm.nih.gov/pubmed/26466783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0930-x
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