Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer

BACKGROUND: PI3K/Akt/mTOR signaling is being actively pursued as a therapeutic target for breast cancer. We sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway markers. METHODS: Intraoperative image-guided core-needle biopsies (CNB), an...

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Detalhes bibliográficos
Main Authors: Meric-Bernstam, Funda, Akcakanat, Argun, Chen, Huiqin, Sahin, Aysegul, Tarco, Emily, Carkaci, Selin, Adrada, Beatriz E., Singh, Gopal, Do, Kim-Anh, Garces, Zerzhinski M., Mittendorf, Elizabeth, Babiera, Gildy, Bedrosian, Isabelle, Hwang, Rosa, Krishnamurthy, Savitri, Symmans, William F., Gonzalez-Angulo, Ana Maria, Mills, Gordon B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112583/
https://ncbi.nlm.nih.gov/pubmed/24895461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1507
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