Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression

Mutations in p53 and RAS potently cooperate in oncogenic transformation and correspondingly these genetic alterations frequently coexist in pancreatic ductal adenocarcinoma (PDA) and other human cancers. Previously we identified a set of genes synergistically activated by combined RAS and p53 mutati...

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Bibliographic Details
Main Authors: Kinsey, Conan, Balakrishnan, Vijaya, O’Dell, Michael R., Huang, Jing Li, Newman, Laurel, Whitney-Miller, Christa L., Hezel, Aram F., Land, Hartmut
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112575/
https://ncbi.nlm.nih.gov/pubmed/24794439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.061
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