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Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype

Understanding the molecular underpinnings of cancer is of critical importance to developing targeted intervention strategies. Identification of such targets, however, is notoriously difficult and unpredictable. Malignant cell transformation requires the cooperation of a few oncogenic mutations that...

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Autors principals: McMurray, Helene R., Sampson, Erik R., Compitello, George, Kinsey, Conan, Newman, Laurel, Smith, Bradley, Chen, Shaw-Ree, Klebanov, Lev, Salzman, Peter, Yakovlev, Andrei, Land, Hartmut
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613942/
https://ncbi.nlm.nih.gov/pubmed/18500333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06973
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