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Modified murine intracranial aneurysm model: aneurysm formation and rupture by elastase and hypertension

INTRODUCTION: Cerebral aneurysms occur in up to 5% of the population. There are several murine models of aneurysms; however, all have limitations and none reproducibly model aneurysm rupture. To fulfill this need, we modified two current rodent aneurysm models to create a murine model which reproduc...

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Bibliographic Details
Main Authors: Hosaka, Koji, Downes, Daniel P, Nowicki, Kamil W, Hoh, Brian L
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112494/
https://ncbi.nlm.nih.gov/pubmed/23943816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/neurintsurg-2013-010788
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