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Interleukin-6 Promotes Murine Estrogen Deficiency-Associated Cerebral Aneurysm Rupture

BACKGROUND: Estrogen deficiency is associated with cerebral aneurysm rupture, but the precise mechanism is unknown. OBJECTIVE: To test the hypothesis that IL-6 is required for the increase in aneurysm rupture rate observed in estrogen-deficient mice. METHODS: We analyzed IL-6 expression in human cer...

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Detalhes bibliográficos
Publicado no:Neurosurgery
Main Authors: Wajima, Daisuke, Hourani, Siham, Dodd, William, Patel, Devan, Jones, Chad, Motwani, Kartik, Fazal, Hanain Z, Hosaka, Koji, Hoh, Brian L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317988/
https://ncbi.nlm.nih.gov/pubmed/31264696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyz220
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