Efficient Generalized Least Squares Method for Mixed Population and Family-based Samples in Genome-wide Association Studies

Genome-wide association studies (GWAS) that draw samples from multiple studies with a mixture of relationship structures are becoming more common. Analytical methods exist for using mixed-sample data, but few methods have been proposed for the analysis of genotype-by-environment (G×E) interactions....

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Hlavní autoři: Li, Jia, Yang, James, Levin, Albert M., Montgomery, Courtney G., Datta, Indrani, Trudeau, Sheri, Adrianto, Indra, McKeigue, Paul, Iannuzzi, Michael C., Rybicki, Benjamin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112407/
https://ncbi.nlm.nih.gov/pubmed/24845555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21811
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