Mode of action of the hemin-controlled inhibitor of protein synthesis.
Despite the finding that the hemin-controlled translational inhibitor in reticulocyte lysates is a cyclic AMP-independent protein kinase that phosphorylates the small subunit of the initiation factor eIF-2, the mechanism of inhibition of translation remained unexplained. Whereas treatment of hemin-c...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1978
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.243 |
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