Mode of action of the hemin-controlled inhibitor of protein synthesis.

Despite the finding that the hemin-controlled translational inhibitor in reticulocyte lysates is a cyclic AMP-independent protein kinase that phosphorylates the small subunit of the initiation factor eIF-2, the mechanism of inhibition of translation remained unexplained. Whereas treatment of hemin-c...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	de Haro, C, Datta, A, Ochoa, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1978
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.243
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